About the Charts

The numbers in the charts come from Federal government vital statistics records, the best available data for cancer and non-cancer deaths. The specific sources are the Surveillance, Epidemiology and End Results Program (SEER, National Cancer Institute) and the National Center for Health Statistics (Centers for Disease Control).

The charts are adapted from work originally published in the Journal of the National Cancer Institute:

Woloshin S, Schwartz LM, Welch HG. The risk of death by age, sex, and smoking status in the United States: putting health risks in contextExternal Web Site Policy. J Natl Cancer Inst. 2008 Jun 18;100(12):845-53.

The website was created in collaboration with Lisa M. Schwartz, MD, MS and Steven Woloshin, MD, MS from the Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, NH.

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About the Numbers

Most of us aren't used to seeing numbers about the chance of dying. A 60-year-old man has a 4 out of 1000 chance of dying from colon cancer in the next 10 years. Is that a big or small chance? To decide, it helps to get perspective by comparing this chance with other chances. Comparing the chance of dying from different diseases helps you to appreciate which are the biggest threats you face (the ones you might want to do something about) and which threats are less worrisome. Compared to his chance of colon cancer, the 60 year old man's chance of dying from coronary heart disease in the next 10 years is much bigger (29 out of 1000); his chances of dying from prostate cancer (3 out of 1000) is about the same, while his chance of dying from rabies is much lower (less than 1 out of 1000).

Another important way to get perspective is to consider the chance of dying from anything (called "all causes" in the charts). It allows you to see how each individual cause of death contributes to the total. Because there are so many causes of death, you can't simply add up the numbers in each column of the charts. So we have a row across the top of the big picture charts with the chance of dying from all causes at each age.

The big picture charts are all about the chance of dying over the next 10 years. While the 10-year time frame is arbitrary, it makes sense to us. It's not too long (it's easy to imagine) and it's not too short (so the chances aren't forced to look too small). And it allows time to do things like change your lifestyle (most importantly not smoking) or consider proven screening testsExternal Web Site Policy - to lower your chances.

Changing the time frame matters a lot. The longer the time, the larger the chance. To see how chances change over time, you can create custom charts which provide the chances over the next 10 years, 20 years or for over a person's remaining life expectancy (how much longer someone that age is expected to live).

The your chances option lets you see the top causes of death for a person based on the sex, race and exact age you select. To show you how things change over time, we also show the top causes for the same person when they were 10 years younger and when they will be 10 years older.

And the special cancer tables give you a different kind of perspective: they let you compare the risk of diagnosis and death for a variety of cancers. For most diseases, getting the disease is much more likely than dying from it. Although many people believe cancer is a death sentence, this is far from the case. By comparing the risk of being diagnosed with a cancer to your risk of death from the cancer you can get a sense of how deadly the cancer really is.

Finally, the numbers in the charts are averages. In health statistics, age and sex are generally the most important predictors of what will happen to you. That's why the charts break down the chances by age and sex. The charts do not account for other important predictors - like a strong family history of a certain disease or various behaviors (like smoking) or exposures (working with asbestos) - which affect your chances too. When reliable methods for generating more personalized estimates become available, we will incorporate them into the charts.

If you want to read more about how to make sense of messages about chance, you can download the book "Know your chances: Understanding health statistic - How to see through the hype in the medical news, ads and public service announcements" (University of California Press) from PubMed Health's Understanding Research Results.External Web Site Policy

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About the Cause of Death Categories

In most cases, we used standard National Center for Health Statistics' 113 most common causes of death categories as defined in the Deaths: Leading Causes reports available from the CDC's National Vital Statistics ReportsExternal Web Site Policy. We modified standard categories, however, in several instances to enhance clinical meaning. For example, the NCHS 113 list includes the category "ischemic heart disease" which consists of deaths from acute myocardial infarction, other acute and chronic ischemic heart disease, and atherosclerotic cardiovascular disease. We modified the list to create a category called "coronary heart disease," which includes all the foregoing "ischemic heart disease" deaths plus deaths from associated complications (eg, congestive heart failure and arrhythmia). In addition, some causes of death have been removed from our list (e.g., "Certain other intestinal infections"). Refer to the Cause of Death Definitions for the ICD-10 codes used to define the causes of death included in this website.

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About the Problems With Death Certificate Data

The accuracy of the charts ultimately depends on accurate attribution of death on death certificates and the methods used by the National Center for Health Statistics to assign the underlying cause of death. Assigning an underlying cause of death for individuals with multiple medical problems is particularly challenging since there is often uncertainty in the chain of events leading to death. It is likely that both under- and over-counting of deaths occurs. Diabetes and hypertension deaths, for example, are probably under-counted: they are often reported as contributing factors rather than as the underlying cause of death.

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Methodology

DevCan- Probability of Developing and Dying from Cancer

Statistical models are used to compute the probability of being diagnosed or dying of cancer from birth or conditional on a certain age. DevCan statistical package is used to compute these probabilities. DevCan takes cross-sectional counts of incident cases from the standard areas of the Surveillance, Epidemiology, and End Results (SEER) Program conducted by the National Cancer Institute, and mortality counts for the same areas from data collected by the National Center for Health Statistics, and uses them to calculate incidence and mortality rates using population estimates from census data for these areas. These rates are converted to the probabilities of developing or dying from cancer for a hypothetical population. Please note that when the program refers to cancer or incidence, it is referring only to the cancer site that you requested.

To obtain additional information about the methodology, please access the following link: http://surveillance.cancer.gov/devcan/.

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Data Source

Incidence data used in these charts were obtained from the 18 registries of the Surveillance, Epidemiology, and End Results (SEER) program for the special cancer section. While mortality data for the same areas collected by the National Center for Health Statistics (NCHS) were used for cancer death chart in the special cancer section. Three most recent years of diagnosis & death (2012-2014) were used for all the calculations.

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Cause of Death Definitions

ICD-10 Coding for Causes of Death available in Risk Tables
Cause of Death ICD-10 Coding
All CausesA00-Y89
Vascular DiseaseI00-I78
Coronary Heart DiseaseI20-I25, I42.0, I42.8, I42.9, I44-I46, I50
Heart Valve DiseaseI00-I02, I05-I09, I33-I39
Heart Muscle DiseaseI40-I41, I42.1-I42.7, I43
Heart Lining DiseaseI30-I32
Heart Rhythm DiseaseI47-I49
Diffuse AtherosclerosisI70
Peripheral Vascular DiseaseI73.9
StrokeI60-I69
Abdominal Aortic AneurysmI71.3-I71.4
Aortic Aneurysm Outside AbdomenI71.0-I71.2, I71.5-I71.9
High Blood PressureI10-I15
InfectionA00-B99, G00, G03, J09-J22, J36, J85-J86, K61, K65, N10-N12, N13.6, N15.1, N30
Pneumonia/FluJ09-J18
BronchitisJ20-J21
AIDSB20-B24
Viral HepatitisB15-B19
TuberculosisA15-A19
Salmonella InfectionsA01-A02
Kidney InfectN10-N12, N13.6, N15.1
Shigellosis and AmebiasisA03, A06
Whooping CoughA37
Scarlet Fever and ErysipelasA38, A46
MeningitisA39, G00, G03
TetanusA34-A35
RabiesA82
SepticemiaA40-A41
SyphilisA50-A53
PolioA80
Tick Related Brain InfectionsA83-A84, A85.2
MeaslesB05
MalariaB50-B54
Chicken Pox & ShinglesB01-B02
DiabetesE10-E14
Malnutrition and Vitamin DeficienciesE40-E64
Lung DiseaseI26-I28, J30-J35, J37-J47, J60-J70, J80-J84, J90-J98
AsthmaJ45-J46
COPDJ40-J44, J47
Lung Disease from Environmental ExposureJ60-J66, J68
Lung Disease due to AspirationJ69
Lung Circulation DiseaseI26-I28
Gastrointestinal DiseaseK00-K14, K20-K31, K50-K52, K55-K60, K62-K64, K66-K68, K70-K77, K80-K87, K90-K95
AppendicitisK35-K38
HerniaK40-K46
Ulcer DiseaseK25-K28
Chronic Liver Disease and CirrhosisK70, K73-K74
Gallbladder DiseaseK80-K82
Blood DiseasesD50-D89
Sickle Cell AnemiaD57
Thalassemia and Other Hereditary AnemiasD55-D56, D58-D59
Other AnemiaD50-D54, D60-D64
Urinary Tract DiseaseN00-N29, N31-N53, N60-N65, N70-N77, N80-N99
Kidney DiseaseN00-N07, N17-N19, N25-N27
Enlargement of the ProstateN40
Pelvic Infections in WomenN70-N76
Accidents & InjuriesU01-U03, V01-Y89
AccidentsV01-X59, Y85-Y86
SuicideU03, X60-X84, Y87.0
HomicideU01-U02, X85-Y09, Y87.1
Criminal Justice SystemY35, Y89.0
WarY36, Y89.1
Complications of Health CareY40-Y84, Y88
Pregnancy and Birth DefectsO00-O99, Q00-Q99
Pregnancy RelatedO00-O99
Birth DefectsQ00-Q99
Neurological DiseaseG04-G99
Alzheimers DiseaseG30
Parkinsons DiseaseG20-G21
CancerC00-C97
Oral Cavity and PharynxC00-C14
EsophagusC15
StomachC16
Colon and RectumC18-C21, C26.0
LiverC22.0-C22.4, C22.7, C22.9
PancreasC25
LarynxC32
Lung and BronchusC34
MelanomaC43
BreastC50
CervicalC53
UterineC54-C55
OvarianC56
ProstateC61
Kidney and Renal PelvisC64-C65
BladderC67
Brain and Other Nervous SystemsC70-C72
Hodgkin LymphomaC81
Non-Hodgkin LymphomaC82-C85, C96.3
LeukemiaC90.1, C91-C95
Multiple MyelomaC90.0, C90.2
ThyroidC73
TestisC62
Kaposi SarcomaC46
MesotheliomaC45

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